Slay the Spire 2 Tier List

Updated for Early Access (March 2025). Rankings based on Ascension 20 win rates, consistency, and overall power level.

S
👁️

Watcher

Stance Master

Highest damage potential with Wrath/Calm stance dancing

💀

Necrobinder

Minion Commander

New character with Doom mechanics and powerful summons

A
⚡

Defect

Orb Manipulator

Reliable scaling with Focus and Lightning/Dark orbs

B
🗡️

Silent

Poison Expert

Strong poison scaling but vulnerable early game

🛡️

Ironclad

Tank

Solid defense but slower than other characters

Ranking Methodology

  • • Win Rate: Consistency across multiple runs
  • • Scaling: Late-game power and Ascension 20 viability
  • • Flexibility: Adaptability to different relics and card pools
  • • Early Game: Survivability in Acts 1-2